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Therefore, existing treatment methods still fail to adequately meet the clinical demand for slowing disease progression and improving non-motor symptoms

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The extended-release formulations offered more stable glucose regulation throughout the day and exhibited enhanced glycaemic control relative to their first-generation equivalents in direct comparison analyses (Nauck and Meier 2019)

doi: 10.3389/fphys.2018.00095 Received 25 October 2017 Accepted 29 January 2018 Published 14 February 2018 Volume 9 - 2018 Edited by Ali Mobasheri, University of Surrey, United Kingdom Reviewed by Felipe Simon, Universidad Andrs Bello, Chile