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Doctors who Science News talked to for this story emphasized the significance of the recent MASH progress, calling this era in the field a watershed moment, and the more than a dozen new medications in development a tidal wave. Rezdiffra may have been the first drug FDA-approved for MASH, but in the next two to three years, Su says, there will be many more
Untested combinations: Novel or less-researched peptides lack even the limited safety information available for established compounds
Cardiovascular, MASH, and OSA indications NC Medicaid retained coverage for Wegovy's cardiovascular risk-reduction (established CVD), MASH (moderate-to-advanced fibrosis), and sleep-apnea indications even after removing obesity coverage on October 1, 2025
Target levels above 400 pg per milliliter
Pedersen, I
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