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4 A meta-analysis of findings from 11 clinical trials (seven that used transcranial direct current stimulation [tDCS], three that used transcutaneous electrical nerve stimulation [TENS], and one that used electroacupuncture of the ear) found electrical stimulation in general reduced Tinnitus Handicap Inventory scores and measures of tinnitus loudness and distress

It has also been reported that 5-amino-1MQ treatment requires an acclimation period, with some subjects reporting decreased exercise tolerance with cardiovascular exercise