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However, when inflammation becomes chronic or damage outpaces repair, problems develop

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doi: 10.1016/j.ejcb.2017.03.004 81 MentleinRGallwitzBSchmidtWE

Starting both medications simultaneously makes it impossible to identify which medication is causing which side effects, makes dose titration dangerous because you cannot isolate responses, and maximizes the risk of overlapping side effects like nausea

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