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Archived from the original on May 29, 2013

If you are uncertain about how long your unopened pen has been out of the fridge, or if it has been exposed to high temperatures, contact your pharmacist or GP surgery for advice before using it

This was supported by Bester et al., who demonstrated that IL-1, IL-6, and IL-8 (proinflammatory cytokines) promote whole-blood hypercoagulability and alter erythrocyte membrane structure

While joint pain is rare, being informed and consulting your doctor about any side effects ensures you can make the best decisions for your treatment