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Gray T, Hoffman RS, Bateman DN

5-Amino-1-methylquinolinium iodide is the lead first-in-class small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT) an enzyme overexpressed in white adipose tissue of obese individuals where it consumes the methyl-donor pool and depletes tissue NAD

Access this chapter Subscribe and save Buy Now Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others Abbreviations AA: Acrylamide FTIR: Fourier transform infrared spectroscopy GAMA: N -acetyl-S-(2-carbamoyl-2-hydroxy-ethyl)-l-cysteine GC-MS: Gas chromatography-mass spectroscopy GSH: Glutathione GST: Glutathione S-transferase HbAA: N -(2-carbamoylethyl)valine HbGA: N -(2-carbamoyl-2-hydroxyethyl)valine HPLC: High-performance liquid chromatography IARC: International Agency of Research on Cancer Iso-GAMA: N -acetyl-S-(1-carbamoyl-2-hydroxy-ethyl)-l-cysteine LC-MS: Liquid chromatography-mass spectroscopy PAH: Polyaromatic hydrocarbons PAM: Polyacrylamide ROS: Reactive oxygen species SOD: Superoxide dismutase Nrf-2: Nuclear factor erythroid 2 TNF: Tumor necrosis factor OD: Optical density SPE: Solid-phase extraction References Achten C, Andersson JT (2015) Overview of polycyclic aromatic compounds (PAC)

Lyophilized peptides are usually stable at room temperatures for several weeks or more, so if they will be utilized within weeks or months such storage is typically adequate, however, it is imperative to avoid repeated freeze/thaw cycles to maintain peptide integrity

At 5mg/mL, those same 25 units only deliver 1.25mg