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Because phentermine is a stimulant, its side effects often include an increased heart rate, elevated blood pressure, dry mouth, nervousness, and insomnia

At the same dose, a 74 kg participant had about 1.4 times the exposure of a 110 kg reference, while a 143 kg participant had about 0.8 times. Weight alone does not set the dose, but it helps explain why the trial mean transfers poorly to bodies outside the studied range

This is a rare and reversible side effect, but the condition is excruciatingly painful

While beautiful scenery helps mood and motivation, sustainable weight loss often requires structured medical support

Mantovani A, Targher G