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AGE-RAGE interaction High glucose promotes the non-enzymatic glycation of proteins, forming AGEs
However, the therapeutic efficacy and safety of SM04690 under long-term or repeated dosing remain unverified, and its effects on other joint-resident cells such as synoviocytes and osteoblasts have not been fully explored
We defined two sets of genes, those either largely devoid of promoter bound NRF2 (Group I, green) or genes with high promoter bound NRF2 (Group II, purple) (Fig
JAMA Otolaryngology Head & Neck Surgery, 131 (11), 970-975
3 , 70ra13 (2011)
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