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Demonstrated herein, a tuned-down anti-Her2 biologic-CD3 TCE retained potent cytotoxicity against cells with high Her2 expression, comparable to its parental high-affinity counterpart, while showing reduced activity against cells with low Her2 levels, demonstrating improved selectivity and safety

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Figure 2 is visibly expressing the effect of iron by causing oxidative damage to the oxyhemoglobin content of hemolysate