This review highlights the therapeutic potential of individual natural compounds, as well as emerging strategies in combinatorial and precision medicine, offering a comprehensive synthesis of current advancements in natural product-based AD therapy
Persistent SASP signaling contributes to local tissue dysfunction and chronic inflammatory microenvironments in aging models
MicroRNAs (miRNAs) have been also shown to play an important role in adipogenesis, IR, and inflammation as previously reviewed [49].Tonicity-responsive enhancer-binding protein (TonEBP), a key transcription factor involved in cellular adaptation to hypertonic stress, has been suggested to influence macrophage activity, adipogenesis, and IS by inhibiting the epigenetic transition of PPAR2 [50]
In this way, the role of autophagy in glaucomatous RGC death is still controversial
1996;128(5 Pt 2):S32-S37 Forsling ML, Wheeler MJ, Williams AJ