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Heres the next section: Legal Status and Disclaimer IGF-1 LR3 is not classified as a controlled substance, but it is not approved for human use by the FDA outside of clinical research settings

Weight cycling, a scenario likely in real-world GLP-1 therapy use due to treatment discontinuation and subsequent weight regain, further increases this risk, as repeated cycles of weight loss and regain are associated with cumulative muscle loss and progressive declines strength [25]

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Timar J, Gyorffy B, Raso E