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Studies were excluded if they met the following exclusion criteria: studies conducted on children, adolescents, or animals, reviews studies, in vitro studies, editorial papers, gray literature, books, conference abstracts, and RCTs conducted without a placebo or control group

Synthetic antioxidants such as butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), and tertiary butylhydroquinone (TBHQ) are commonly employed as preservatives or additives by pharmaceutical, cosmetic, and food companies [32]

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