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[] A phase II research study including males with localized PCa demonstrated that a daily dosage of 40 mg of aglycone isoflavones for a duration of 3 to 6 weeks before surgery was well tolerated

#### Indications: **Vitamin B12 Deficiency:** Treatment of vitamin B12 deficiency due to malabsorption, dietary insufficiency, or increased physiological needs (e.g., pregnancy, lactation)

0,75 mg

Day 20 : Higher doses (50mg and 100mg) maintain results well

Such findings align with preclinical models showing that prolonged ethanol exposure induces persistent neuroadaptations in mood-regulating circuits, including the prefrontal cortex, hippocampus, and amygdala (Hasin and Grant 2015)