In this guide, we explain what these peptides are, what the science says so far, the risks you should know about, and what changed with the FDA in 2026
doi: 10.1155/2020/2576823
GI symptoms, including excessive salivation, dysphagia, constipation, esophageal motility disorders, and gastric abnormalities, occur many years before the appearance of motor symptoms and may be associated with an increased risk of developing PD [112]
When used in topical formulations, the most commonly reported issues are localised and mild, and may include: Skin irritation or redness at the site of application Contact dermatitis in individuals with sensitive skin or known peptide sensitivities Scalp itching or tingling , which may be transient The following precautions are advised: Avoid application to broken, inflamed, or irritated skin , and keep the product away from the eyes and mucous membranes
I mean, and there's also the different issues in the brain versus the liver