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As discussed previously, elevated KYNA levels are consistently associated with impairments in learning, memory, and executive function, effects that are largely attributed to 7nAChR antagonism

doi: 10.1038/s41467-023-37368-1 78 SousaGFCarpesRMSilvaCAOPereiraMEPSilvaACVFCoelhoVAGSet al

Whether or not it actually works is unclear as of 2019

Data limitations: No completed human efficacy trial exists for any indication, and the literatures short observation windows mean long-term safety in either animals or humans remains unestablished

British Association of Dermatologists living guideline for managing alopecia areata