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There are a few reasons for this

In summary, combining microbial and chemical synthesis methods while avoiding routes that use cyanides yields the best results

Zllner, Tapper, et al., 2022) has shown one-to-one amplitude-ratio soft constraint between the GABA amplitude and the co-edited macromolecules at 3.0 ppm (1to1GABAsoft in Osprey) performs better for edited MRS regarding to modeling performance

Additionally, the prevalence of OSAHS was markedly higher in postmenopausal females not undergoing hormone replacement therapy than in both premenopausal females and postmenopausal females receiving hormone replacement therapy, particularly when controlling for confounding variables such as body mass index (BMI) and neck circumference (5, 6)

A short medical history conversation is the first step