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The siRNA-based lipid-lowering drug inclirisan also demonstrates a reduction in Lp(a) levels, which has been confirmed in ORION 10 and ORION 11 [215]

455 Therefore, sildenafil holds promise as a therapeutic option for HAPH patients, warranting further investigation to address its efficacy and safety

Importantly, we observed significantly better preservation of ATP pools at supercooled temperatures (Fig