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65 In another well-designed study, 187 mg of a similar peppermint oil product taken three times daily before meals for eight weeks led to a significant improvement over placebo with regard to abdominal discomfort, abdominal pain, and quality of life, but not in terms of diarrhea, constipation, or bloating

The recommended daily intake is 1,000-1,200mg for adults

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Some medications that commonly require dose adjustment include: Aminoglycosides and Vancomycin Enoxaparin Digoxin Gabapentin and Pregabalin Metformin Allopurinol Colchicine Levetiracetam Clinical Pearl: Renal dose adjustment is not just about reducing the doseit may involve extending the dosing interval, avoiding certain medications altogether, or closely monitoring drug levels and patient response

I also think sun protection is important