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They can adjust the dosage based on the individual's response and ensure safe administration

Thom SR, Fisher D, Xu YA, Garner S, Ischiropoulos H

Conditions That Increase Injection Site Discomfort Higher concentrations: At higher concentrations of GHK-Cu, the concentration of positively charged GHK-Cu molecules at the injection site increases, amplifying the localised pH disturbance and the associated discomfort

however, its application is significantly constrained by life-threatening cardiotoxic effects and the potential for developing cardiomyopathy

If evening dosing causes any issues (some users report vivid dreams when taking DSIP too close to bedtime), experimenting with afternoon administration is reasonable