In NSCLC, MEG3 suppresses tumor proliferation and metastasis via the miR-21-5p/PTEN and MDM2/p53 axes, while in pulmonary hypertension, it promotes vascular remodeling by sponging miR-328-3p and upregulating IGF1R, highlighting its dual context-dependent roles in tumor suppression and vascular dysfunction [109,110,111]
Thymosin 4-derived peptides alleviate neuroinflammation and neurite atrophy in both in vitro models and in vivo 5 FAD mice: A potential therapy for memory improvement in Alzheimer's disease
Int J Immunopathol Pharmacol
The 0.9% benzyl alcohol in BAC water acts as a preservative, inhibiting bacterial growth that could occur when the septum is punctured repeatedly
Factor in the rapid clearance mechanism, whereby nasally-applied drugs are cleared with a half-life of approximately 21 minutes, and its clear why only certain peptides can be used nasally