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Garcia-Carbonell, R

Notably, even in the absence of FOXO4 FH , we observed an -helical population of TAD1, which slightly increased in presence of FOXO4 FH

Cultured mammalian cells were treated with menadione or BSO: menadione increases oxidation of glutathione, while BSO inhibits synthesis of cellular GSH

Notably, bone marrow lipid content is markedly increased in precursor MM states (MGUS and SMM) compared to healthy controls (Panaroni et al., 2022)

Laboratory protocol development for FOXO4-DRI research requires careful consideration of dosing strategies, administration timing, and experimental endpoints to maximize scientific insights while ensuring reproducible results