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Maintaining a robust antioxidant defense system is essential for supporting cellular health for both the mother and the baby

Removal of genomic DNA and reverse transcription were carried out with ReverTra Ace qPCR RT Kit (Toyobo, Osaka, Japan) according to the manufacturer's instructions

NAC may help by supporting antioxidant defenses and reducing oxidative stress, though its effects vary depending on the population and fertility issue being studied.32 In men, one randomized trial found that 600mg of NAC, selenium, or the combination improved semen parameters, with the combination producing stronger effects than either ingredient alone.23 In women undergoing assisted reproduction, NAC has also been studied for oocyte and embryo quality, though this research is still relatively early and not definitive.24 PCOS NAC has attracted particular interest in PCOS, where insulin resistance, inflammation, and oxidative stress often overlap.17 Researchers think NAC may help by improving insulin sensitivity and reducing oxidative stress, which may, in turn, support ovulation and reproductive function

doi: 10.1080/00032710802568655 54 Trujillo-CceresSJTorres-SnchezLBurguete-GarcaAIOrbe OrihuelaYCVzquez-SalasRAlvarez-TopeteEet al

(2026) FDA Federal Register (2026) WADA 2026 Prohibited List USADA