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When switching to an SC injection device, either during or after clinical trials, the following scenarios are possible: IV vial to SC injection device during clinical development IV vial to SC injection device post-launch SC vial to SC injection device during clinical development SC vial to SC injection device post-launch SC injection device to SC injection device post-launch

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High-Resolution Mass Spectrometric data were obtained from a Bruker microTOF mass spectrometer (Ettlingen, GER)

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