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A reduction in CYPOR protein levels prevented NFT-dependent accumulation of Nrf2 protein and partially attenuated the NFT-dependent increase in glutathione levels
83,284 Immunomodulatory therapies targeting specific components of the immune response offer promising avenues for reducing nerve inflammation and promoting repair (Fig
Compared to the control which was not infected by IBDV, the transcript levels of ggt and gsr genes were significantly increased by 2.43 0.16-fold and 1.82 0.08-fold, respectively, while the transcript levels of gss did not significantly change, indicating that the GSH utilization pathway was significantly elevated, while the GSH synthesis pathway was not significantly changed (Fig
Early impairment of NGF/TrkA signaling in AD can lead to reduced synaptic vesicle secretion and decreased presynaptic protein expression, resulting in presynaptic functional impairment of cholinergic primary neurons [88]
The lipid-lowering effects appear to be indirect rather than through direct lipid metabolism
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