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DSIP may more broadly influence deep sleep architecture and stress response Benzodiazepines carry significant risks of dependency and cognitive side effects

Elevated GIP levels and duodenal K cell hyperplasia (62) have also been reported in HFD-treated mice, while Gipr deficiency protects mice from HFD-, leptin deficiency- or ovariectomy-induced weight gain (63, 64)

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elegans largely present as self-fertile hermaphrodites but can also be mated by males, making it a versatile model to investigate the complex relationship between reproduction, resource allocation, and longevity