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Epicutaneous (EC) immunization with type II collagen (COLL II) induces CD4(+) CD8(+) T suppressor cells that protect from collagen-induced arthritis (CIA)

Materials H-His(Trt)-OMeHCl, H-Lys(Boc)-OMeHCl, H-Lys-OMe2HCl, ((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tri(pyrrolidine-1-yl)phosphonium hexafluorophosphate(V) (PYBOP), 2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate (HBTU), 1-hydroxy benzotriazole hydrate (HOBT), GHK and 4-carboxyphenyl boric acid were obtained from Bide Pharmatech Ltd (Shanghai, China)

Leaky gut and bone and joint autoimmunity Leaky gut syndrome has also been found to contribute to the development of autoimmune reactions targeting bone and joint tissue

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