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10.1002/advs.202403992 34 Dubreuil-MauriziC.PoinssotB

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doi: 10.1016/j.mito.2007.02.006

In the MD stable conformation of hTYR, GSH_c forms hydrogen bonds with residues in the L2 and L4 regions, spanning these regions and ultimately chelating with both copper ions

By controlling T cell metabolic pathways like glycolysis, OXPHOS, FAO, and amino acid metabolism, these tactics may effectively regulate T cell differentiation, function, and immune response, offering a fresh approach to the treatment of autoimmune diseases ( Figure 3 )