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The maximal therapeutic dose recommended by the FDA is 4 g/day

coli strain BL21 (DE3) or strain XL1-Blue and purified by Ni-NTA affinity chromatography as described previously 14,26,35,88

To clarify the role of KU-57788-induced mitophagy in its anti-ATC effects, we employed several inhibitors: the autophagy initiation inhibitor 3-Methyladenine (3-MA), the autophagolysosome inhibitor chloroquine (CQ), and the V-ATPase inhibitor bafilomycin A1 (BafA1)

Evidently, SARS-CoV-2 infection could elicit auto-inflammatory and autoimmune disorders such as Guillain-Barr syndrome (GBS), autoimmune hemolytic anemia, immune thrombocytopenic purpura, and Kawasaki disease (KD) 12,229,230