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There is also evidence that SCFAs decline the release of TNF- from neutrophils (Lee et al., 2019), which is also one of the typical pro-inflammatory cytokines that trigger subclinical inflammation

For weight management, NICE technology appraisals TA875 (semaglutide/Wegovy) and TA664 (liraglutide/Saxenda) specify that treatment must be initiated within specialist weight management services, with specific BMI thresholds and time-limited treatment periods

Now, newer evidence suggests that GLP-1s may help with depression and anxiety, too

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However, symptoms that last beyond 2-3 days or come with vomiting suggest your dosage is too high or the supplement doesn't suit your body chemistry