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187,188 Multiple clinical trials have found that exercise therapy may slow the rate of kidney function loss or, in some cases, improve kidney function

Dose-response effects on HbA(1c) and bodyweight reduction of survodutide, a dual glucagon/GLP-1 receptor agonist, compared with placebo and open-label semaglutide in people with type 2 diabetes: a randomised clinical trial

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Regarding antioxidants, GSH level was significantly reduced in the STZ group (10.47 0.69 nmol/g protein) versus controls (27.18 3.92 nmol/g protein) ( p 0.05)

While the efficacy of the drugs is clear to see, usage comes with side effects, including gastrointestinal issues, muscle and bone loss, and lower micronutrient intakes