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Therefore, considering the overlapping yet distinct roles of insulin and IGF-1 in the brain, disruptions in their signaling pathways due to IR may contribute to the neurobiological mechanisms underlying depression in individuals with T2DM

In older adults, lifestyle modifications remain a significant challenge [11, 20], and the increasing burden of NCDs further underscores the strategic role of pharmacotherapy as part of a comprehensive strategy of the obesity management

With consistent use, many individuals notice progressive improvement in skin brightness, texture, and clarity

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If fatigue doesnt improve after a few weeks, follow up with your clinician to confirm the diagnosis, check whether the dose and form are appropriate, and look for other contributors such as iron deficiency, thyroid issues, sleep problems, or medication effects