Exposure to greater than 25 mg may precipitate a hypertensive crisis , marked by a rapid rise in blood pressure (often exceeding 180/120 mmHg), chest pain, and acute confusion
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Accumulating evidence implicates the LPA signaling axis in therapy resistance across multiple cancers
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First, the crosstalk network between distinct ferroptosis-regulating pathways (System Xc GSHGPX4 axis, lipid peroxidation, iron metabolism, and epigenetic regulation) remains poorly definedwhether these pathways act in a hierarchical, synergistic, or compensatory manner in different phases of I/R injury (ischemia vs