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It must include assessment of nutritional status before treatment to identify patients with malnutrition whose risks may only be mitigated with additional support. Fiorella DiCarlo, RDN, CDN, of FiorellaEatsTV, told Healthline that GLP-1s slow gastric emptying and motility, which causes people to feel full and lose their appetite

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Strains that support GI motility, gut comfort, and regularity may offer modest support during the adjustment period, but the evidence base for probiotic effects on drug-induced constipation specifically is limited