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Approximately 40% of subjects received influenza vaccine prior to entering the study

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Examples include high-dose vitamin A or retinoids (which can be hepatotoxic in excess), green tea extract catechins (associated with rare cases of liver injury), kava, or high-dose niacin

Key data indicate that knocking out GIPR in GABAergic (VGAT+) neurons ablated the ability of GIPR mono-agonists to drive weight loss on their own and for dual GLP-1R/GIPR agonists to produce additive weight loss beyond GLP-1R agonists alone [31]