did not lose weight on semaglutide Non-Response: Why Some Don't Not Losing Weight on Semaglutide?

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These include gastrointestinal symptoms (nausea, vomiting, diarrhoea, constipation), injection site reactions, and, rarely, pancreatitis (severe upper abdominal pain radiating to the back) or gallbladder problems

Genetic variants like GIPR rs1800437 and GLP1R rs6923761 directly influence GLP-1 signaling efficiency, meaning some patients achieve dramatic weight loss within 34 months while others show steady progress over 812 months

Weight loss exceeding 1 kg per week sustained over four or more weeks warrants reassessment of the combination's appetite effects

When he was done, he opened up to questions from the floor