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GLP-1 medications like semaglutide have shown remarkable efficacy for weight management, with clinical trials demonstrating up to 22% body weight reduction over 68 weeks

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However, because semaglutide changes how your body processes food and oral medications, there are several important timing and side-effect considerations to keep in mind

Medically reviewed by Dr Kathryn Basford Last reviewed: 27 Jan 2026 Wegovy has been proven to be an effective weight loss treatment, but it still takes time for it to have an effect

This includes highly refined grains like white bread, white rice, and sugary cereals, as well as foods rich in added sugars such as soda, fruit juices without fiber, candy, and sweetened desserts