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The development of dependable biomarkers to estimate therapy response and enhance patient selection constitutes another substantial unmet need, since individual responses to GLP-1 treatments might differ markedly

Most important bioactive compounds secreted by enteroendocrine L cells in the gut due to nutrient uptake are glucagon-like peptides (GLPs) including GLP-1 and GLP-2

The new PepD construct (BBa_K3206015) was designed to have lower expression using a Bba_I1051 promoter

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L-carnitine mainly promoted the metabolism of fatty acids, amino acids, and carbohydrates, while trimetazidine mainly enhanced the metabolism of amino acids and carbohydrates