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Dehydration also impairs lymphatic drainage, causing subcutaneous water retention that masks fat loss on the scale, leading patients to believe the protocol isn't working when it is

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References References TripleHormone-Receptor Agonist Retatrutide for Obesity A Phase 2 Trial Retatrutide in patients with obesity and MASLD Body composition outcomes of Retatrutide in patients with obesity Retatrutide in type 2 diabetes efficacy and glucose response Sub-analysis of the Phase 2 trial in Nature Medicine ClinicalTrials.gov: Ongoing global studies on weight loss, cardiovascular risk, and diabetes outcomes Synonyms: Retatrutide, 2381089-83-2, EX-A7826E, GTPL13769 Research & background Independent, research-focused reading

These changes indicate the peptide is active even before hair changes become apparent