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This is largely due to delayed diagnosis leading to detection in the advanced stages

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The core mechanism of TB-500 is tissue regeneration through three pathways: angiogenesis (forming new blood vessels), cell migration (moving repair cells to the injury site), and anti-inflammatory action

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The co-primary outcomes of this study were changes in arterial stiffness and kidney oxygenation, with a specific focus on carotid-femoral pulse wave velocity as a measure of arterial stiffness