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Conclusion Despite significant progress in the management of cardiac iron overload in -thalassemia patients, cardiovascular disease remains the leading cause of death in this population

During Hp-induced chronic gastric inflammation, there is an increased tissue turnover that predisposes to an excessive rate of cell proliferation and may result in excessive frequency of mitotic errors and increased rate of mutagenesis

Matsui M, Oshima M, Oshima H, Takaku K, Maruyama T, Yodoi J et al (1996) Early embryonic lethality caused by targeted disruption of the mouse thioredoxin gene

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