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56,57 Although direct injection of CCND2-overexpressing hPSC-CMs is not applicable in humans due to safety concerns, this strategy underscores the potential of pro-proliferative interventions to significantly increase the efficacy of hPSC transplantation

18 GLP-1 RAs were initially approved by the FDA for the treatment of type 2 diabetes based on phase 3 trials demonstrating superiority in reducing hemoglobin A 1c and improving cardiovascular outcomes compared with other antihyperglycemic medications