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After reaching a plateau around week 40 to 44, participants maintained their weight through week 48 with minimal regain of only 0.8kg on average

Most gastrointestinal side effects such as bloating and gas are mild and self-limiting, typically resolving within days to weeks as the gut microbiome adjusts to the introduced bacterial strains

Since the GLP-1 receptor is often present in the membrane of neural processes, including the axon terminals (Farkas et al., 2021), Rinaman said, it is possible that the GLP-1 receptor made by those cortical and hippocampal neurons is trafficked to their axon terminals in subcortical regions that do receive GLP-1 input

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What labs should I check before and during treatment