tirzepatide without diabetes VisualAbstract: Superior to Semaglutide in Obese Adults Who Is a Good Candidate

Approved in December 2025, the pill delivers the efficacy of semaglutide with the convenience of a daily tablet

Images were analysed semi-automatically with FIJI software and AutoNeuriteJ plugin to measure neurite length

The needle is short and thin, and the injection is subcutaneous (just under the skin), not into muscle or a vein

It is important to note that Wegovy is intended as an adjunct to a reduced-calorie diet and increased physical activity, not as a standalone solution for weight management

The fact that low vitamin D levels in obese individuals may further exacerbate venous dysfunction by impairing nitric oxide bioavailability and increasing oxidative stress has been reported in the literature [17, 38, 44], but no studies investigated, to the best of our knowledge, the NOS isoforms local expression in the varicose veins