20,21 The authors have demonstrated that within macrophages of HIV+ individuals, GSSG was more heavily favoured and decreased levels of rGSH correlated with a significant increase in the growth of M
ATP-based luminescence assays, such as the CellTiter-Glo 2.0 Assay, are the preferred platform for HTS drug screening because they offer the highest sensitivity (detecting 15100 cells/well), the simplest protocol (single reagent addition, 10-minute read time), and the lowest coefficient of variation across plate formats
In the 1990s, liquid chromatographymass spectrometry (LC-MS) with electrospray ionization (ESI), atmospheric pressure chemical ionization (APCI), or atmospheric pressure photoionization (APPI) revolutionized bioanalysis in analytical toxicology [59]
Large and symptomatic nodules or goiters can be treated with surgery when the more conservative approaches have proven fruitless
Community-acquired pneumonia (CAP)