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You should always check the manufacturer's label for specific guidelines, but this is the general industry standard

Although epidemiologic studies have shown an association between vascular disease and hyperhomocysteinemia, large randomized controlled trials have shown that lowering homocysteine levels in these patients does not reduce the number of myocardial infarctions or strokes, or improve mortality rates

Follow-up Re-check glucose markers and relevant metabolic markers after 4-8 weeks or sooner if symptoms change

After opening a vial, refrigerate and keep the top covered

A 12 mg blend reconstituted with bacteriostatic water yields about 4 mg/mL