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However, benchmarking against SUSTAIN-6 flagged disagreement for the effect on all-cause mortality, highlighting potential residual confounding for this secondary endpoint that could reflect preferential prescribing in patients for whom clinicians anticipated limited life expectancy

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The phase 3 trials also tested a 4mg maintenance dose in addition to the 9mg and 12mg doses

In developing mouse offspring exposed to mercuric chloride (HgCl2), curcumin administration significantly attenuated anxiety and depression-like behaviors while normalizing biochemical markers of toxicity (Mohammad Abu-Taweel and Al-Fifi, 2021)

This well-studied application has made strides in the treatment of IR, serving as a new and upcoming innocuous supplement that, when coupled with subtle lifestyle changes, can ameliorate IR