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Because whilst the potential pain benefits are interesting, there are specific reasons why the hypermobility and Ehlers-Danlos population needs to approach GLP-1 drugs with considerably more caution than the general public

Most patients lose 3 to 8% of their starting body weight by week 12

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High-fat diet in early life triggers both reversible and persistent epigenetic changes in the Medaka fish (Oryzias latipes)

The press release compares this to DHT-semaglutides AE rate of 79.2%