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The maximum approved dose produces the greatest weight loss in clinical trials but also the highest side effect incidence

However, skin retraction follows a different timeline: 0-8 weeks : Initial shrinking as pregnancy hormones decrease 3-6 months : Gradual improvement in skin elasticity 6-12 months : Maximum natural skin retraction usually achieved Beyond 12 months : Any remaining loose skin is unlikely to improve significantly without intervention Hormonal influences play a role during this recovery period

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Braun M, Khan ZT, Khan MB, Kumar M, Ward A, Achyut BR, Arbab AS, Hess DC, Hoda MN, Baban B, et al