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aureus at low microgram-per-milliliter concentrations

Male C57BL/6J mice (aged 7 weeks) were purchased from Huafu Kang Biotechnology Co., Ltd

When comparing the responders from the CRWP group ( n = 12) to the non-responders in the same group ( n = 7), there was a significant difference in age with the responders being significantly older (4.23 0.22 years) than non-responders (3.48 0.18 years

Specifically, the increased loss of RBCs leads to the increased formation of bilirubin, which further triggers eryptosis by enhancing both Ca 2+ influx, SMase activation, and ceramide production, thus creating a vicious cycle