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Its also the stage that originally sparked scientific interest in Delta Sleep-Inducing Peptide (DSIP)

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Considering the mechanistic overlap in the development and progression of CKD in type 1 and type 2 diabetes, there exists a strong rationale for simultaneously developing novel CKD therapies for use in both type 1 diabetes and type 2 diabetes and studying the repurposing of existing type 2 diabetes CKD therapies for the treatment of CKD in people with type 1 diabetes

Adjusting the rate of dose escalation or temporarily maintaining a lower dose may improve tolerability whilst still achieving therapeutic benefit

Zhao, Y., Yang, L., Wang, X